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1

Blood biomarkers for memory: toward early detection of risk for Alzheimer disease, pharmacogenomics, and repurposed drugs

Niculescu, A. B., Le-Niculescu, H., Roseberry, K., Wang, S., Hart, J., Kaur, A., Robertson, H., Jones, T., Strasburger, A., Williams, A., Kurian, S. M., Lamb, B., Shekhar, A., Lahiri, D. K., Saykin, A

Journal:

Molecular Psychiatry

Year:

2019

Language:

english

File:

PDF, 1.66 MB

english, 2019

2

Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs

Le-Niculescu, H., Roseberry, K., Levey, D. F., Rogers, J., Kosary, K., Prabha, S., Jones, T., Judd, S., McCormick, M. A, Wessel, A. R., Williams, A., Phalen, P. L., Mamdani, F., Sequeira, A., Kurian,

Journal:

Molecular Psychiatry

Year:

2019

Language:

english

File:

PDF, 1.51 MB

english, 2019

3

O45. Blood Biomarkers for Possible Early Detection of Risk for Alzheimer Disease (AD)

Niculescu, Alexander, Le-Niculescu, Helen, Roseberry, Kyle, Wang, Sophia, Lahiri, Debomoy, Saykin, Andrew

Journal:

Biological Psychiatry

Year:

2019

Language:

english

File:

PDF, 46 KB

english, 2019

4

Convergent functional genomics of genome-wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms

H. Le-Niculescu, S.D. Patel, M. Bhat, R. Kuczenski, S.V. Faraone, M.T. Tsuang, F.J. McMahon, N.J. Schork, J.I. Nurnberger Jr., A.B. Niculescu III

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Year:

2009

Language:

english

File:

PDF, 684 KB

english, 2009

5

Discovery and validation of blood biomarkers for suicidality

Le-Niculescu, H, Levey, D F, Ayalew, M, Palmer, L, Gavrin, L M, Jain, N, Winiger, E, Bhosrekar, S, Shankar, G, Radel, M, Bellanger, E, Duckworth, H, Olesek, K, Vergo, J, Schweitzer, R, Yard, M, Ballew

Journal:

Molecular Psychiatry

Year:

2013

Language:

english

File:

PDF, 3.03 MB

english, 2013

6

P2-260: BLOOD BIOMARKERS FOR MEMORY: TOWARDS EARLY DETECTION OF RISK FOR ALZHEIMER DISEASE, PHARMACOGENOMICS, AND REPURPOSED DRUGS

Niculescu, Alexander B., Le-Niculescu, Helen, Wang, Sophia, Lamb, Bruce T., Lahiri, Debomoy K., Saykin, Andrew J.

Journal:

Alzheimer's & Dementia

Year:

2019

File:

PDF, 257 KB

2019

7

Identification and Characterization of GIV, a Novel G i/s -interacting Protein Found on COPI, Endoplasmic Reticulum-Golgi Transport Vesicles

Le-Niculescu, H., Niesman, I., Fischer, T., DeVries, L., Farquhar, M. G.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 1.98 MB

english, 2005

8

Candidate genes, pathways and mechanisms for alcoholism: an expanded convergent functional genomics approach

Rodd, Z A, Bertsch, B A, Strother, W N, Le-Niculescu, H, Balaraman, Y, Hayden, E, Jerome, R E, Lumeng, L, Nurnberger, J I, Edenberg, H J, McBride, W J, Niculescu, A B

Journal:

The Pharmacogenomics Journal

Year:

2007

Language:

english

File:

PDF, 566 KB

english, 2007

9

Psychiatric blood biomarkers: avoiding jumping to premature negative or positive conclusions

Niculescu, A B, Levey, D, Le-Niculescu, H, Niculescu, E, Kurian, S M, Salomon, D

Journal:

Molecular Psychiatry

Year:

2015

Language:

english

File:

PDF, 1.94 MB

english, 2015

10

Mood, stress and longevity: convergence on ANK3

Rangaraju, S, Levey, D F, Nho, K, Jain, N, Andrews, K D, Le-Niculescu, H, Salomon, D R, Saykin, A J, Petrascheck, M, Niculescu, A B

Journal:

Molecular Psychiatry

Year:

2016

Language:

english

File:

PDF, 2.85 MB

english, 2016

11

Convergent functional genomics: A Bayesian candidate gene identification approach for complex disorders

B. Bertsch, C.A. Ogden, K. Sidhu, H. Le-Niculescu, R. Kuczenski, A.B. Niculescu

Journal:

Year:

2005

Language:

english

File:

PDF, 171 KB

english, 2005

12

Genetic risk prediction and neurobiological understanding of alcoholism

Levey, D F, Le-Niculescu, H, Frank, J, Ayalew, M, Jain, N, Kirlin, B, Learman, R, Winiger, E, Rodd, Z, Shekhar, A, Schork, N, Kiefe, F, Wodarz, N, Müller-Myhsok, B, Dahmen, N, Nöthen, M, Sherva, R, Fa

Journal:

Translational Psychiatry

Year:

2014

Language:

english

File:

PDF, 1.60 MB

english, 2014

13

Assessing Risk of Future Suicidality in Emergency Department Patients

Brucker, Krista, Duggan, Carter, Niezer, Joseph, Roseberry, Kyle, Le-Niculescu, Helen, Niculescu, Alexander B., Kline, Jeffrey A., Alter, Harrison

Journal:

Academic Emergency Medicine

Year:

2018

Language:

english

File:

PDF, 224 KB

english, 2018

14

The Mammalian Calcium-Binding Protein, Nucleobindin (CALNUC), Is a Golgi Resident Protein

Ping Lin, Helen Le-Niculescu, Robert Hofmeister, J. Michael McCaffery, Mingjie Jin, Hanjo Hennemann, Tammie McQuistan, Luc De Vries and Marilyn Gist Farquhar

Journal:

The Journal of Cell Biology

Year:

1998

Language:

english

File:

PDF, 5.84 MB

english, 1998

15

Convergent Functional Genomics of bipolar disorder: From animal model pharmacogenomics to human genetics and biomarkers

H. Le-Niculescu, M.J. McFarland, S. Mamidipalli, C.A. Ogden, R. Kuczenski, S.M. Kurian, D.R. Salomon, Ming T. Tsuang, J.I. Nurnberger Jr., A.B. Niculescu

Journal:

Neuroscience & Biobehavioral Reviews

Year:

2007

Language:

english

File:

PDF, 725 KB

english, 2007

16

Convergent integration of animal model and human studies of bipolar disorder (manic-depressive illness)

Helen Le-Niculescu, Sagar D Patel, Alexander B Niculescu

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 396 KB

english, 2010

17

Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs

Niculescu, A. B., Le-Niculescu, H., Levey, D. F., Roseberry, K., Soe, K. C., Rogers, J., Khan, F., Jones, T., Judd, S., McCormick, M. A., Wessel, A. R., Williams, A., Kurian, S. M., White, F. A.

Journal:

Molecular Psychiatry

Year:

2019

File:

PDF, 1.91 MB

2019

18

Dissecting Suicidality Using a Combined Genomic and Clinical Approach

Niculescu, Alexander B, Le-Niculescu, Helen

Journal:

Neuropsychopharmacology

Year:

2017

Language:

english

File:

PDF, 73 KB

english, 2017

19

Withdrawal of Survival Factors Results in Activation of the JNK Pathway in Neuronal Cells Leading to Fas Ligand Induction and Cell Death

Le-Niculescu, Helen, Bonfoco, Emanuela, Kasuya, Yoshitoshi, Claret, Francois-Xavier, Green, Douglas R., Karin, Michael

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 2.92 MB

english, 1999

20

The P-value illusion: How to improve (psychiatric) genetic studies

Alexander B. Niculescu, Helen Le-Niculescu

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Year:

2010

Language:

english

File:

PDF, 61 KB

english, 2010

21

Evidence for genetic association ofRORBwith bipolar disorder

Casey L McGrath, Stephen J Glatt, Pamela Sklar, Helen Le-Niculescu, Ronald Kuczenski, Alysa E Doyle, Joseph Biederman, Eric Mick, Stephen V Faraone, Alexander B Niculescu, Ming T Tsuang

Journal:

Year:

2009

Language:

english

File:

PDF, 598 KB

english, 2009

22

Genetic risk prediction and neurobiological understanding of alcoholism

Levey, D F, Le-Niculescu, H, Frank, J, Ayalew, M, Jain, N, Kirlin, B, Learman, R, Winiger, E, Rodd, Z, Shekhar, A, Schork, N, Kiefe, F, Wodarz, N, Müller-Myhsok, B, Dahmen, N, Nöthen, M, Sherva, R, Fa

Journal:

Translational Psychiatry

Year:

2014

File:

PDF, 51 KB

2014

23

Blood biomarkers for memory: toward early detection of risk for Alzheimer disease, pharmacogenomics, and repurposed drugs

Niculescu, A. B., Le-Niculescu, H., Roseberry, K., Wang, S., Hart, J., Kaur, A., Robertson, H., Jones, T., Strasburger, A., Williams, A., Kurian, S. M., Lamb, B., Shekhar, A., Lahiri, D. K., Saykin, A

Journal:

Molecular Psychiatry

Year:

2019

File:

PDF, 1.66 MB

2019

24

Convergence of recent GWAS data for suicidality with previous blood biomarkers: independent reproducibility using independent methodologies in independent cohorts

Niculescu, A. B., Le-Niculescu, H.

Journal:

Molecular Psychiatry

Year:

2019

Language:

english

File:

PDF, 254 KB

english, 2019

25

Identifying blood biomarkers for mood disorders using convergent functional genomics

Le-Niculescu, H, Kurian, S M, Yehyawi, N, Dike, C, Patel, S D, Edenberg, H J, Tsuang, M T, Salomon, D R, Nurnberger, J I, Niculescu, A B

Journal:

Molecular Psychiatry

Year:

2008

Language:

english

File:

PDF, 255 KB

english, 2008

26

Towards understanding and predicting suicidality in women: biomarkers and clinical risk assessment

Levey, D F, Niculescu, E M, Le-Niculescu, H, Dainton, H L, Phalen, P L, Ladd, T B, Weber, H, Belanger, E, Graham, D L, Khan, F N, Vanipenta, N P, Stage, E C, Ballew, A, Yard, M, Gelbart, T, Shekhar, A

Journal:

Molecular Psychiatry

Year:

2016

Language:

english

File:

PDF, 3.11 MB

english, 2016

27

Convergence of recent GWAS data for suicidality with previous blood biomarkers: independent reproducibility using independent methodologies in independent cohorts

Niculescu, A. B., Le-Niculescu, H.

Journal:

Molecular Psychiatry

Year:

2019

File:

PDF, 254 KB

2019

28

M7 TOWARDS PRECISION MEDICINE FOR MOOD DISORDERS: OBJECTIVE ASSESSMENT AND TARGETED THERAPEUTICS FOR DEPRESSION AND MANIA

Niculescu, Alexander, Le-Niculescu, Helen, Roseberry, Kyle, Levey, Daniel, Phalen, Peter, Nurnberger, John, Shekhar, Anantha, Kurian, Sunil

Journal:

European Neuropsychopharmacology

Year:

2019

File:

PDF, 70 KB

2019

29

PhenoChipping of psychotic disorders: A novel approach for deconstructing and quantitating psychiatric phenotypes

Alexander B. Niculescu, Len L. Lulow, Corey A. Ogden, Helen Le-Niculescu, Daniel R. Salomon, Nicholas J. Schork, Michael P. Caligiuri, James B. Lohr

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Year:

2006

Language:

english

File:

PDF, 373 KB

english, 2006

30

Understanding and predicting suicidality using a combined genomic and clinical risk assessment approach

Niculescu, A B, Levey, D F, Phalen, P L, Le-Niculescu, H, Dainton, H D, Jain, N, Belanger, E, James, A, George, S, Weber, H, Graham, D L, Schweitzer, R, Ladd, T B, Learman, R, Niculescu, E M, Vanipent

Journal:

Molecular Psychiatry

Year:

2015

Language:

english

File:

PDF, 5.01 MB

english, 2015

31

Convergent Functional Genomics: what we have learned and can learn about genes, pathways, and mechanisms

Niculescu, Alexander B, Le-Niculescu, Helen

Journal:

Neuropsychopharmacology

Year:

2010

Language:

english

File:

PDF, 99 KB

english, 2010

32

Towards understanding the schizophrenia code: An expanded convergent functional genomics approach

H. Le-Niculescu, Y. Balaraman, S. Patel, J. Tan, K. Sidhu, R.E. Jerome, H.J. Edenberg, R. Kuczenski, M.A. Geyer, J.I. Nurnberger Jr, S.V. Faraone, M.T. Tsuang, A.B. Niculescu

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Year:

2007

Language:

english

File:

PDF, 2.00 MB

english, 2007

33

Identification of blood biomarkers for psychosis using convergent functional genomics

Kurian, S M, Le-Niculescu, H, Patel, S D, Bertram, D, Davis, J, Dike, C, Yehyawi, N, Lysaker, P, Dustin, J, Caligiuri, M

Journal:

Molecular Psychiatry

Year:

2009

Language:

english

File:

PDF, 1.15 MB

english, 2009

34

Phenomic, Convergent Functional Genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism

H. Le-Niculescu, M.J. McFarland, C.A. Ogden, Y. Balaraman, S. Patel, J. Tan, Z.A. Rodd, M. Paulus, M.A. Geyer, H.J. Edenberg, S.J. Glatt, S.V. Faraone, J.I. Nurnberger, R. Kuczenski, M.T. Tsuang, A.B.

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Year:

2008

Language:

english

File:

PDF, 1.01 MB

english, 2008

35

Identifying blood biomarkers for mood disorders using convergent functional genomics

Le-Niculescu, H, Kurian, S M, Yehyawi, N, Dike, C, Patel, S D, Edenberg, H J, Tsuang, M T, Salomon, D R, Nurnberger, J I, Niculescu, A B

Journal:

Molecular Psychiatry

Year:

2009

Language:

english

File:

PDF, 112 KB

english, 2009

36

Coming to grips with complex disorders: Genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics

S.D. Patel, H. Le-Niculescu, D.L. Koller, S.D. Green, D.K. Lahiri, F.J. McMahon, J.I. Nurnberger Jr, A.B. Niculescu III

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Year:

2010

Language:

english

File:

PDF, 451 KB

english, 2010

37

Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs

Niculescu, A. B., Le-Niculescu, H., Levey, D. F., Roseberry, K., Soe, K. C., Rogers, J., Khan, F., Jones, T., Judd, S., McCormick, M. A., Wessel, A. R., Williams, A., Kurian, S. M., White, F. A.

Journal:

Molecular Psychiatry

Year:

2019

Language:

english

File:

PDF, 1.91 MB

english, 2019

38

M7 TOWARDS PRECISION MEDICINE FOR MOOD DISORDERS: OBJECTIVE ASSESSMENT AND TARGETED THERAPEUTICS FOR DEPRESSION AND MANIA

Niculescu, Alexander, Le-Niculescu, Helen, Roseberry, Kyle, Levey, Daniel, Phalen, Peter, Nurnberger, John, Shekhar, Anantha, Kurian, Sunil

Journal:

European Neuropsychopharmacology

Year:

2019

Language:

english

File:

PDF, 70 KB

english, 2019

39

Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction

Ayalew, M, Le-Niculescu, H, Levey, D F, Jain, N, Changala, B, Patel, S D, Winiger, E, Breier, A, Shekhar, A, Amdur, R, Koller, D, Nurnberger, J I, Corvin, A, Geyer, M, Tsuang, M T, Salomon, D, Schork,

Journal:

Molecular Psychiatry

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

40

Convergent functional genomic studies of omega-3 fatty acids in stress reactivity, bipolar disorder and alcoholism

Le-Niculescu, H, Case, N J, Hulvershorn, L, Patel, S D, Bowker, D, Gupta, J, Bell, R, Edenberg, H J, Tsuang, M T, Kuczenski, R, Geyer, M A, Rodd, Z A, Niculescu, A B

Journal:

Translational Psychiatry

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

41

Convergent functional genomics of anxiety disorders: translational identification of genes, biomarkers, pathways and mechanisms

Le-Niculescu, H, Balaraman, Y, Patel, S D, Ayalew, M, Gupta, J, Kuczenski, R, Shekhar, A, Schork, N, Geyer, M A, Niculescu, A B

Journal:

Translational Psychiatry

Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

42

Precision medicine for suicidality: from universality to subtypes and personalization

Niculescu, A B, Le-Niculescu, H, Levey, D F, Phalen, P L, Dainton, H L, Roseberry, K, Niculescu, E M, Niezer, J O, Williams, A, Graham, D L, Jones, T J, Venugopal, V, Ballew, A, Yard, M, Gelbart, T, K

Journal:

Molecular Psychiatry

Year:

2017

Language:

english

File:

PDF, 7.02 MB

english, 2017

43

O45. Blood Biomarkers for Possible Early Detection of Risk for Alzheimer Disease (AD)

Niculescu, Alexander, Le-Niculescu, Helen, Roseberry, Kyle, Wang, Sophia, Lahiri, Debomoy, Saykin, Andrew

Journal:

Biological Psychiatry

Year:

2019

File:

PDF, 46 KB

2019

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